Best Ergonomic Mouse in 2021 | Great For Usage!

With the right ergonomic mouse in the hand, you can reduce orthopedic injuries. Furthermore, you can compensate for a condition you might currently have. RMS (Repetitive Motion Syndrome) has been around for ages. From the farmer to the city laborers digging trenches suffered from RMS.

These days office workers, video game players, and more suffer from the same ailment all because they are not using the correct computer mouse. So if you want to prevent this disorder from happening to you, look at the top 10 best ergonomic mice in 2021 available with us here. You can minimize permanent damage by using an ergonomic one compared to a regular mouse.

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The Best Ergonomic Mouse in 2021

Top Best Ergonomic Mouse You Can Pair With Your Computer!

10. Cherry Precision

Cherry Precision

If you have a tight budget, or have bought a keyboard online, the Cherry Precision MC 4000 is a greatly affordable add-on. This ergonomic mouse has a three-button with scroll wheel design. The dots per inch are 1,200 with a precisely controlled cursor. The amazing thing is you can use it with your left or right hand.

CHERRY MC 1000 Corded Mouse, Black
German-engineered 3-button computer mouse with scroll wheel; Lightweight + ambidextrous design: suitable for both left and right-handed user

Last update on 2020-04-13 / Affiliate links / Images from Amazon Product Advertising API


  • Low-cost laser mouse
  • Suitable to use with point and click games
  • Great to use for normal office work
  • Comfortable in the hand


  • Not responsive enough to FPS gamers

9. Anker Vertical Optical Mouse

Anker Vertical Optical Mouse

We know how difficult times are and you have a limited budget. Here you can find the affordable Anker ergonomic mouse with a vertical design. The optical mouse has a 1000/1600 dots per inch (DPI) resolution that is more sensitive compared to a standard mouse. This offers you precise tracking on different surfaces. For webpage, browsing it has a next/previous button and great for gamers. The USB cables 4.9ft and only weighs 5.3 oz.

Anker Ergonomic Optical USB Wired Vertical Mouse 1000/1600 DPI, 5 Buttons CE100
1.5m/4.9ft USB cable length, product dimensions: 120*62.8*74.8 mm; product weight: 5.3 oz.

Last update on 2020-04-13 / Affiliate links / Images from Amazon Product Advertising API


  • 18-Month warranty
  • Looks classy
  • Great thumb rest
  • Astounding grip
  • Five buttons for improved control
  • Affordable


  • The scroll does not always respond

8. Logitech Silent Plus

Logitech Silent Plus

Another similar affordable ergonomic mouse is the M330 Silent Plus from Logitech. This one is in the same price range as the Anker. Logitech reduced the clicking sound by 90%. The device automatically connects to your PC by using a wireless receiver. The wireless range works up to 33-feet and you get a two-year battery life. To improve the battery use it has an auto sleep function. While the optical tracking works on most surfaces. However, you do need to take note that this is a right-handed mouse.

Last update on 2020-04-13 / Affiliate links / Images from Amazon Product Advertising API


  • Affordable
  • While quiet you can still feel the click
  • Comfortable but might be a bit small for some users


  • Not recommended as a gaming mouse

7. Logitech Triathlon

Logitech Triathlon

If you do have the money and can spend a little extra, choose the M270 Triathlon from Logitech. The amazing thing is you can pair this ergonomic mouse with up to three computers and switch between them with a touch of a button. The scroll wheel or shift to click-to-click scrolling is perfect for flying through documents and web pages. The buttons on the Triathlon can withstand up to 10M clicks. According to Logitech, the battery life use is up to 24 months. To connect wireless you receive included a Unifying Receiver or use Bluetooth Smart Technology.

Last update on 2020-04-13 / Affiliate links / Images from Amazon Product Advertising API


  • Buttons are customizable
  • Bluetooth connection
  • Connects fast
  • Excellent scroll wheel
  • Can switch between devices
  • Silent


  • None noted

6. Microsoft Bluetooth Ergonomic Mouse

Microsoft Bluetooth Ergonomic Mouse

Microsoft offers you three amazing colors black, dark red, and Azul/blue when buying the 3600 ergonomic mouse. The device has a compact design with Bluetooth connection. For navigation, it has a 4-way scroll wheel and works on most surfaces. Another benefit of this computer mouse is the ambidextrous design suitable for both left- and right-hand users. The device is Bluetooth 4.0 compatible. The battery life use is up to 12 months. The network range is up to 32-feet.

Microsoft Bluetooth Mobile Mouse 3600, Azul (PN7-00021)
Compact Design for ultimate portability; 4-way scroll wheel for navigating up, down, left and right

Last update on 2020-04-13 / Affiliate links / Images from Amazon Product Advertising API


  • Zero lags
  • Suitable for left- and right-hand users
  • Auto-sleep function to save battery power
  • Comfortable
  • Has a rubberized grip


  • None noted

5. Apple Magic Mouse 2

Apple Magic Mouse 2

Now for something a bit more expensive in the ergonomic mouse collection, the Apple Magic Mouse 2. What makes this MAC mouse unique is the rechargeable battery and simple design. You can use it on multiple surfaces and tracks with ease as it has an optimized foot. The device pairs automatically with your MAC Bluetooth connection and the battery last up to a month of use. You can use this wireless mouse via Bluetooth or with the lightning USB cable included. Another benefit is the one-year warranty offered by Apple.

Apple Magic Mouse 2 (Wireless, Rechargable) - Silver
Magic Mouse 2 is ready to go right out of the box and pairs automatically with your Mac.; Magic Mouse 2 is ready to go right out of the box and pairs automatically with your Mac.

Last update on 2020-04-13 / Affiliate links / Images from Amazon Product Advertising API


  • The rodent automatically pairs with the device
  • Charges quickly
  • Comfortable to use
  • Works smoothly


  • Only made to use with MAC systems

4. Logitech MX Anywhere 2

Logitech MX Anywhere 2

The Logitech MX Anywhere 2 you can buy in three amazing color design Meteorite, Navy, and Stone. Whether you are an office worker or gamer the ergonomic mouse tracks anywhere. You can use it on a glass to high-gloss surfaces. With the dual wireless design, it connects to Windows and MAC operating systems. The device works via the Pico Unifying receiver and connects up to three devices at the same time. The batteries rechargeable and lasts up to two months of use. You can reassign the button functions making it highly customizable.

Last update on 2020-04-13 / Affiliate links / Images from Amazon Product Advertising API


  • Connects without issues
  • Can charge the battery while using the mouse
  • Has an on/off switch
  • Pairs with three computers


  • The included micro USB cable is a bit on the short side

3. Razer DeathAdder Chroma

Razer DeathAdder Chroma

If you are a gamer, you will know the Razer rodent range. The DeathAdder Chroma is one of the best ergonomic mice with a perfect design. For fast moving speeds, it has a 10,000dpi optical sensor and moves up to 200-inches per second with 50g acceleration. Another thing this rodent can do is Z-axis tracking when used on low surfaces. An extra amazing thing is the Chroma lighting to customize colors with up to 16.8M available.

Last update on 2020-04-23 / Affiliate links / Images from Amazon Product Advertising API


  • Has a great grip
  • Lightweight
  • Customizable colors
  • Great to use for FPS and RPG games
  • Accurate sensor
  • You receive notifications to update the firmware


  • Double clicks but solved with a firmware update

2. Logitech MX Master

Logitech MX Master

Whether you do office work or a gamer and have the money to spend, spend it on the Logitech MX Master. The wireless mouse offers you cross control between computers. You can copy and paste documents and content between PCs. The batteries rechargeable and offers you up to 70-days of use. The scroll wheels shifts from auto to click-to-click and allows you side-to-side scrolling. The ergonomic mouse has a hand-sculpted shape and fits comfortably in the hand.

Logitech MX Master Wireless Mouse – High-precision Sensor, Speed-adaptive Scroll Wheel, Thumb Scroll Wheel, Easy-Switch up to 3 Devices
Unique thumb wheel: For horizontal navigation and advanced gestures; Easy switching between computers with the touch of the button

Last update on 2020-04-13 / Affiliate links / Images from Amazon Product Advertising API


  • Feels great in the hand
  • Has a thumb rest
  • Free scroll setting
  • Comfortable side buttons
  • Customizable
  • Wireless


  • When using the mouse wheel in normal mode it is loud

1. Mad Catz R.A.T. ProX Gaming Mouse

Mad Catz R.A.T. ProX Gaming Mouse-ergonomic mouse

For the crème de la crème of all rodents and a steep price, you can buy the Mad Catz R.A.T. ProX gaming mouse. This ergonomic mouse has swappable sensors to use with normal office work or gaming. The scroll wheel pivots sideways for pinpoint precision and you can even adjust the tension of the wheel or change them with other wheels. The structure of the device is magnesium alloy, carbon fiber, and titanium. You get a pinkie grip, palm/thumb rest and the entire mouse conforms to your hand. This is a gamer’s mouse to enjoy any type of online games. Furthermore, you have 90 programmable commands with 10 programmable buttons and 9 modes.

Last update on 2020-04-13 / Affiliate links / Images from Amazon Product Advertising API


  • Easy to setup
  • Magnetic attachments making customization easier
  • Astounding software
  • Simple and comfortable in the hand
  • Lightweight


  • Some issues when restarting your computer
  • The company that made the rodent has gone bust

What is an Ergonomic Mouse?

Ergonomic can mean anything for different people, but the most important thing is that using an ergonomic mouse needs to be comfortable. Furthermore, it can mean the computer mouse has an odd shape and addresses medical issues when working or gaming.

Therefore, the PC mouse has a design to provide you with comfort and efficiency at the same time. Thus, manufacturers have created the top 10 best ergonomic mice on the list with large grips, outstanding contours, and thumb rests making using them less painful than your standard mouse.

So whether you are a laid-back user or gamer, you will benefit from using one of the models on the list to remove repetitive strain and carpal tunnel syndrome.

Furthermore, you can customize the mouse to prevent RSI that is a common computer-related injury after some time of using it continuously.

What are the benefits of using an ergonomic mouse?

Using an ergonomic mouse offers you loads of benefits as you spend most of your time on the computer. Your work has made sure you have an ergonomic desk and chair, so you need an ergonomic mouse as well for the following beneficial reasons:

  • Reduces Carpal Tunnel Syndrome and RSI – using the ergonomically designed mouse leaves you without the pains as it adjusts the position and movement of the wrist relieving pressure on your vital nerves. The same applies to a repetitive strain injury, and it helps reduce the risk.

  • Made to the natural form of your hand and movement styles – choosing the right one helps resume the natural position of your hand.

  • Helps if you have arthritis – with arthritis, moving the hands difficult and painful with the ergonomic mouse allows you to move with ease.

  • Keeps your hand at a proper angle, especially the vertical mouse as it relieves stress on the nerves and tendons.

  • You can use it with any hand if you buy an ambidextrous mouse and makes a considerable difference to angle your hand correctly.

How do you hold an ergonomic mouse the correct way?

Best Ergonomic Mouse In 2021

While you have the best ergonomic mouse on the market, you still need to hold it the right way to prevent RSI. Here are some tips you can follow:

  • Start by placing your palm on the base but make sure it does not touch the surface of the desk.

  • Let your fingers lay over the buttons and mouse without feeling the strain.

  • Move your whole arm and not only the wrist as it allows your stronger muscles to do all the work.

  • Make sure your elbows bent at a 90° angle, leaving the arm in a natural and neutral position.

  • When clicking makes sure your hand holds the mouse loosely as over-pressing causes strain in the tendons.

  • Always take a break from your work or game to help relax all your muscles.

  • Lastly, place the mouse in a position that your arms kept at 90-degrees with both your elbows beside your sides.

Reasons to Use an Ergonomic Mouse

The ergonomic mouse designs made with the user in mind, and we have some excellent motivations as to why you need one:

  • Helps prevent twisting of the wrist that is a joint function found using a standard mouse.

  • It offers you less grip than a traditional mouse as helps prevent tension in the muscles.

  • Alleviates existing pain in the arms lessening problems when working for hours.

  • Prevents future injuries from taking place as it has a great design.

  • It comes with an innovative construction as the design changes to fit in with your needs.

How Does an Ergonomic Mouse Work?

Best Ergonomic Mouse In 2021

Depending on the type of ergonomic mouse you buy, you can get an odd sensation the first time you use it. When it comes to the vertically designed model, the device is turned at a 57-degree angle to help reduce wrist strain.

Furthermore, you get thumb docks rubberized and give a natural use of alleviating pain in hand. You get a balanced comfort with intuitiveness without the chunkiness’ to the design and look appealing at the same time.

On the other hand, the construction offers you incredible detail to float naturally with your body leaving your arms down by your sides and the wrist parallel to the desk. So if you do not want to feel tired after a long day of work or gaming, choose one of the top 10 best ergonomic mice on the list today.

Final Thoughts

By buying, one of the top 10 ergonomic mice in 2021 available is not a magic wand. What it will do is to prevent future injuries. The rodents reviewed here have ergonomic features to help reduce intensity or injuries to your arm and hands. So if you want to take better care of your hands while working or playing games it is best to use a mouse designed for comfort making your life easier and preventing injuries.

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